Sentence examples for protein function and also from inspiring English sources

The thrill of discovery has been accompanied, however, with the sobering appreciation that human genomes are burdened with a large number of rare and ultra rare variants, thereby posing a significant challenge in dissecting both the effect of such alleles on protein function and also the biological relevance of these events to patient pathology.

Comprehensive analysis of post-translational processing events in STM 14028 identified more than 130 signal peptide and N-terminal methionine cleavage events critical for protein function and also revealed a large and complex repertoire of post-translational chemical modifications, including those known to influences various cell processes and several novel chemical modifications.

Protein function and location also are consistent with a premitochondrial origin.

As described in the Supplementary Material, we considered the various different types of binding sites as a single united binding region important for protein function and we also considered each binding site type separately.

For understanding protein function and location, and also for various practical applications (e.g. overexpression), identification of the correct N-terminus is important.

The possible effects of the mutation to the TPO mRNA splicing activity, protein function, and expression were also investigated.

However, changes in protein function and gene regulation may also highlight genetic changes in orthologous genes that have given rise to phenotypic innovation across Dictyostelid evolution (see, for example, Fig. 1b).

134, 135 Interestingly, breast cancer-specific alternative splicing is not restricted to splicing defects resulting in loss of protein functions, and may also include modifications that generate proteins with new functions.

HelicoBase hosts a total of 13 species and 166 genome sequences of Helicobacter spp. Genome annotations such as gene/protein sequences, protein function and sub-cellular localisation are also included.

Integrated approaches that not only account for DNA and RNA aberrations but also document protein function and biochemistry are clearly the next technical horizon [ 60].

We also further investigated OsSND2 protein function and downstream genes.