Exact(5)
After inactivation of virB, the greatest protein expression change was observed in the outer membrane proteins.
Further analysis by mutagenesis or dose-dependent studies is needed to confirm a relationship between this protein expression change and the changes in fatty acid composition.
The study of pretreatment and post-treatment samples of 28 patients revealed that the protein expression change in IGFBP5, TFF3 or both was significantly associated with change in tumor volume.
TELI and PELI quantify the accumulative altered gene or protein expression change over the exposure period for a given gene (TELIgene, PELIgene), pathway (TELIpathway, PELIpathway), or for the overall DNA damage and repair pathway ensemble library (TELIgeno, PELIgeno).
Such layered curation and annotation of hypoxia-related proteins could be useful for better understanding of both the value of proteomics study in hypoxia and hypoxia-related research and the biological meaning of protein expression change under varying hypoxic conditions and tissue types.
Similar(55)
Protein expression changes were expressed as the mean of the four statistically significant expression ratios.
However, in multiple repeat experiments normalized to protein expression changes, cells expressing iKR PR consistently exhibited reduced PARP cleavage relative to cells expressing iWT PR.
Protein expression changes are not isolated events, we therefore hypothesized that differentially expressed CYB5A protein may interact with others and play a role in oncogenesis.
Modest or strong PEPD overexpression was detected at 24 h after transfection of a plasmid expressing human PEPD, but neither ErbB2 tyrosine phosphorylation nor ErbB2 protein expression changed following PEPD overexpression.
Selected protein expression changes were verified using Western blotting.
Status epilepticus induces a cascade of protein expression changes contributing to the subsequent development of epilepsy.
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