Sentence examples for protein expression and function and from inspiring English sources

These observations are consistent with the concept of "oncogene addiction" [19] to AR protein expression and function, and document that such castrate-resistant prostate cancer cells remain addicted to AR signaling for their malignant growth [1], [9].

An enriched presence of STRs in the regulatory region of the calcium signaling machinery has not previously been reported and may have significant consequences for protein expression and function and consequently disease.

Studies to demonstrate the functional effects of AON treatments on DYSF protein expression and function in cells from patients P1 and P2 are currently underway.

These mutations resulted in disruption or annihilation of proper protein expression and function in each subject.

Goal for the transfection is to study the regulation of gene as well as protein expression and function [23].

As the GR-α and GR-β isoforms originate from alternative splicing of the same gene, the only accurate way of specifically quantifying the GR-β isoform is using qPCR, which precludes information about both protein expression and function.

In this review article, the discussion focuses on the efficiency and practical applicability of using this computerized inhalation exposure system in inducing significant changes in brain protein expression and function as compared to other nicotine delivery methods.

However, regulation of p27Kip1 protein expression and function is predominantly through post-translational modifications that alter both the cellular localization and the extent of E3 ubiquitin ligase-mediated degradation.

To investigate this hypothesis, N-glycosylation sites were engineered at different positions on the extracellular linkers of Kv1.2 to determine the effects of N-glycans on channel surface protein expression and function.

This map has deep and broad implications for protein expression and function in cellular systems, particularly in understanding complex human diseases (e.g., obesity, arthritis and cardiovascular diseases).

Post-translational processing and degradation are regulatory mechanisms controlling protein expression and function [18], [19].