Sentence examples for protein expression abnormalities from inspiring English sources

By comparing the proteomic pattern in T1D and T1D+ESRD patients, it appeared that protein expression abnormalities are consistently present in both groups at a different degree.

S. K. Keay and coworkers review urothelial cell abnormalities, including structural changes, altered gene and protein expression, functional abnormalities, abnormal cell proliferation, and others, in different lower urinary tract symptoms.

It is well-recognised that alterations in p53 protein expression cause abnormalities in cell cycle regulation (Agami and Bernards, 2000).

The primary objective was to test prognostic/predictive markers covering relevant protein expression and genetic abnormalities.

We examined 50 human primary breast tumours for stathmin mRNA and protein expression and screened for abnormalities in the chromosome region harbouring the stathmin gene.

Since previous 2D-DIGE studies have reported abnormalities of protein expression profiles in tumour-adjacent normal tissue [ 22], we have also extended this analysis to normal mucosa tissue.

Specific signaling pathways are thought to drive adaptive versus maladaptive programs of gene and protein expression that contribute to these abnormalities and the balance between these may determine whether the heart fails [204 206].

All of these findings are consistent with loss of Fhit protein expression being as frequent an abnormality in lung cancer pathogenesis as are p53 and p16 protein abnormalities and that such loss occurs independently of the commitment to the metastatic state and of most other molecular abnormalities.

Vascular risk factors that are associated with an increased chance of developing AD might result in either an infiltration of peripheral macrophages into the brain, or increased signaling through the BBB to cause an abnormality in protein expression and upregulation.

These experiments provide evidence that Tat protein expression is sufficient to mediate cognitive abnormalities seen in HIV-infected individuals.

These findings highlight an innovative strategy for localizing pre-malignant lesions within the epithelium based on suspected alterations in protein expression rather than on gross architectural abnormalities, and the results suggest that the approach may have potential to enhance the diagnostic specificity of endoscopy in the clinical setting.