Sentence examples for protein disruption from inspiring English sources

However, as we observe BSA denaturation with CD spectroscopy and binding to a scavenger receptor known to bind disrupted BSA, it is likely that protein disruption, rather than altered epitope exposure, is the main reason for the binding of BSA NP complexes formed from cationic NPs to scavenger receptors.

Apart from TVBN, two indicators of protein disruption are loss of sulphydryl group and production of carbanyl group.

This was used with a functional assay for protein disruption to perform high-throughput analysis of crRNA activity and specificity.

The sigma E factor is regulated by a multistep protease system that senses protein disruption [ 38].

Seeking POF genes has to date largely focused on coding variants, presuming plausible protein disruption.

VEGF perturbs TJ integrity by decreasing OCLN and ZO-1 expression and causing CLDN5 and ZO-1 protein disruption [ 50].

Further we detected fast TJ protein disruptions which could be partly blocked by caspase-3 inhibition with Z-DEVD-fmk.

In both methodological approaches we observed rapid TJ protein disruptions after 30 min of oxygen and glucose deprivation or middle cerebral artery occlusion, which were accompanied by strong caspase-3 activation in brain endothelial cells (BEC).

TrdH showed high homology to LuxR family transcriptional regulatory proteins, disruption of which abolished the production of tirandamycins, indicating that TrdH is a positive regulator for tirandamycin biosynthesis.

On the other hand, TrdK showed high homology to TetR-family transcriptional regulatory proteins, disruption of which significantly increased the yields of tirandamycins almost one-fold, implicating that TrdK is a negative regulator for tirandamycin biosynthesis.

What will trigger intra-protein disruption of charge-charge interactions and replace with another charge-charge interaction involving RNA sequence?