Sentence examples for protein complex composition from inspiring English sources
As patterns of H3K27me3 enrichment and PcG protein complex composition are only partially conserved between plants and animals5, it is not clear whether in plants repression by PcG proteins involves chromatin compaction.
Thus, 5-HT2CR neurotransmission is malleable at transcriptional (eg, editing and alternative splicing), translational (eg, synthesis and post-translational modifications), and topological (eg, trafficking and protein complex composition) levels, which are elegantly controlled and responsive to internal and external stimuli.
Small-molecular fluorescent probes are widely used to detect target protein location and function, identify protein complex composition in biological processes of interest.
The inference of the protein complex composition and of its molecular details can also provide relevant clues for the development and the design of drugs.
MyoD protein complex composition was then analyzed by mass spectrometry (MS) and western blot (WB).
Systematic investigation of protein complex composition and network analysis will provide new insights to drive development of rationally improved strategies to manipulate the balance between Nrf2 and NF-κB responses under both physiological and disease conditions.
For example, how does the presence of overexpressed MYC protein affect complex composition and function, especially in the context of other activated oncogene proteins such as RAS?
Another limitation is encountered with protein complexes whose composition and function may vary according to the context and conditions (Kühner et al., 2010).
Next, we analyzed the results for the F0/F1 ATPase protein complex whose subunit composition, i.e., relative protein abundance was well studied [ 19, 20].
However, although MS is powerful and allows, in principle, for the detection of many copurifying proteins in a fraction, it remains difficult with MS to distinguish specific from nonspecific interactions and to detect quantitative changes in protein complex abundance and composition without direct visualization of the proteins in gels [ 16- 18].
Our data reveal that the dysferlin protein complex has a dynamic composition as a function of myogenic differentiation.
