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We investigate the results of the constraint-based analysis tool to predict protein activities and identify active regulations in the network.
This leads to similar protein amounts, but may lead to different protein activities, because Brn3a represents the wild-type form and BRAF the constitutively activated mutated form.
Zhu, H. et al. Global analysis of protein activities using proteome chips.
Protein kinases (PKs) have evolved as the largest family of molecular switches that regulate protein activities associated with almost all essential cellular functions.
The impaired protein activities by 280 nm LEDs might be one of the reasons that inhibited reactivation.
Understanding mechanisms of information processing in cellular signaling networks requires quantitative measurements of protein activities in living cells.
Extensive in the brains of higher organisms, alternative splicing might be the primary mechanism for generating the spectrum of protein activities that support complex brain functions.
However, these approaches mostly overlook the incorporations of post-translational modifications, which nature extensively uses for modulating protein activities in vivo.
To detect the presence of antibodies to the proacrosin/acrosin system and to evaluate their effect on the sperm acrosomal protein activities in women consulting for infertility.
HIF protein activities are induced in many types of tumours, which are generally associated with tumour cell growth and progression (Torti and Torti, 2013).
Using GST as a control, the assay also demonstrated the inability of the fusion protein to interfere with recombinant protein activities.
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