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In addition, it is unclear whether nicorandil, a KATP channel opener, used as hyperpolarizing cardioplegia or added in hyperkalemic cardioplegic solution may protect endothelial function during cardiac surgery.
Furthermore, DPP-4 inhibitors protect endothelial function through a GLP-1-dependent mechanism.
In experimental studies, ivabradine has been shown to protect endothelial function.
It has been suggested that antioxidant components in certain food groups can limit oxidative damage and thereby protect endothelial function (Moreno and Mitjavila 2003).
The aim of this study is to explore if GLP-1 can protect endothelial function and can reduce inflammation when hypoglycemia is recovered with hyperglycemia, and if this protective action is related to a decrease in oxidative stress.
In addition, a comprehensive study (by one researcher, C.J). of the pharmacological actions of all 48 types of herbs involved in TCM showed that these herbs can improve or protect endothelial function.
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Tian XY, Wong WT, Wang N, Lu Y, Cheang WS, Liu J, et al. PPARdelta activation protects endothelial function in diabetic mice.
Our findings would shed a novel insight into the potential mechanism by which diosgenin protected endothelial function against inflammatory insult.
Cheang WS, Tian XY, Wong WT, Lau CW, Lee SS, Chen ZY, et al. Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5′ adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor delta pathway.
Cheang, W. S. et al. Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5′ adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor delta pathway.
This study was designed to determine if a brief 3-h exposure to metformin protects endothelial function against the effects of hyperglycaemia.
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