Your English writing platform
Discover LudwigExact(1)
These genetic tests reveal that low, but detectable, levels of MEI-S332 at the centromere can protect cohesion.
Similar(58)
The Shugoshin (Sgo) protein family helps to ensure proper chromosome segregation by protecting cohesion at the centromere by preventing cleavage of the cohesin complex.
The correlation between the effects of mutations on binding PP2A in vitro and on protecting cohesion in vivo implies that the interaction of PP2A with Sgol2's coiled coil is essential for protecting cohesin from separase at the first meiotic division.
Why is it important to protect centromeric cohesion during meiosis I? Cohesin-mediated sister chromatid cohesion is essential for proper attachment of sister kinetochores to microtubules emanating from the opposite poles.
Second, the stated premise of the law--to protect unit cohesion and combat effectiveness--is not supported by any scientific studies.
When he and I talked about the military's ban on gay, lesbian, and bisexual people serving openly, he described it as an embarrassment to the armed forces that couldn't be justified, and easily dismissed the idea that it was meant to protect "unit cohesion".
Whatever is responsible for preventing centromeric Rec8 from degradation in meiosis I? The Shugoshin (Sgo) family of proteins has been demonstrated to protect centromeric cohesion during mitosis and meiosis in fission yeast [9].
Previous studies suggested that the mere presence of shugoshin PP2A at centromeres might not be sufficient to protect centromeric cohesion [4 7].
10.7554/eLife.01133.004 Figure 2. Sgol2-PP2A interaction is required to recruit PP2A to kinetochores and protect centromeric cohesion at the first meiotic division.
DOI: http://dx.doi.org/10.7554/eLife.01133.004 10.7554/eLiFigure3..005 Figure 3. Sgol2-PP2A, but not Sgol2-Mad2, isterequiredis required to protect centromeric cohesion at the first meiotic division.
BioGPS (http://biogps.org/ goto=genereport&id=68549) reports strong Sgol2 expression in cell lines and tissues with actively dividing cells, such as the testis and bone marrow, supporting a function for shugoshin-like 2 to protect centromeric cohesion.
More suggestions(1)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com