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We found no statistically significant effect on prosthesis migration.
Results No differences in prosthesis migration, pain scores, range of motion, and subjective outcome were found after 2 years.
We investigated whether celecoxib, a selective Cox-2 inhibitor, increases prosthesis migration in total knee replacement (TKR).
Our hypothesis was that celecoxib, a selective Cox-2 inhibitor, increases prosthesis migration in total knee replacement.
Serial radiographs were compared to assess for periprosthetic osteolysis, lucent lines, bone loss, prosthesis migration, and soft tissue swelling.
However, the cumulative survival with prosthesis migration as an endpoint was substantially lower than in patients with normal renal function, due to stem migration not associated with osteolysis.
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If the prosthesis migrates (rotates) around this tip marker, no migration is measured although the prosthesis actually does migrate.
On the other hand, several postsurgical complications are also described in the literature, such as deep infection [1, 2, 3, 4, 10], wound healing disorders [3, 5, 6], dislocation [1, 2, 4, 5, 6], fractures [1, 4, 6, 10], heterotopic ossification [3, 4], nerve palsies [2, 4, 6], prosthesis cranial migration [2, 5, 10], and limb-length discrepancy [4, 6].
We did not perform a randomized study comparing the uncemented Corail stem with a cemented prosthesis, because migration patterns would obviously differ.
Since loosening of a prosthesis starts with migration, knowledge on migration is important as it could predict future loosening or gain more insight about the fixation [ 25].
Radiographs demonstrated no evidence of prosthesis loosening or migration and no erosion of the lateral tibial plateau.
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