Sentence examples for prospectively testing from inspiring English sources

This approach of identifying a derivation cohort and then prospectively testing the resulting model developed is a much more rigorous approach than simply defining and using the model without a confirmatory cohort.

An alternative strategy would be to use longitudinal designs and multivariate models (for example, logistic regression) that are capable of prospectively testing whether emotional distress predicts treatment outcome while controlling for potential confounders.

Additional criteria that could have been applied include prospective validation, stating the mathematical technique used to develop the rule, clear definition and blinded assessment of predictor variables and outcomes, and prospectively testing the effect of the rule in clinical practice [ 1].

With an array of new agents and predictive biomarkers to investigate, the time for further randomised trials to compare neoadjuvant endocrine treatment with conventional chemotherapy in a broad spectrum of patients with ER+ breast cancer has probably passed – particularly if the trial under consideration is not prospectively testing a predictive biomarker for endocrine responsiveness.

Hazard statements are quantitative, but even after 30 years none of the models has been prospectively tested (for agreement with later earthquakes).

Population pharmacokinetic and pharmacodynamic parameters were estimated by means of nonlinear regression analysis in the first 20 subjects, then prospectively tested in the last 10 subjects.

We prospectively tested two promising methotrexate-based regimens, one more intensive and a milder regimen, for primary CNS lymphoma in the elderly population, who account for most patients.

We therefore set out to develop and prospectively test a comprehensive method to assess both medical provider and organizational performance during a disaster simulation.

The study utilized a predictive model derived from one subset of the study population, and prospectively tested in the other subset to predict the presence of neuropathy.

In this article, we review in detail the 2 human studies that have prospectively tested whether helminth infections protect against allergy.

The aim of the current study was to prospectively test the assumption that pain-related fear in acute stages successfully predicts future disability.