Exact(2)
Using a commercially available immunoassay, circulating CAIX was assessed in prospectively archived serial serum samples collected during combined-modality neoadjuvant treatment of LARC patients and correlated to histologic tumour response and progression-free survival (PFS).
Specifically, we employed prospectively archived serial serum samples collected during the neoadjuvant treatment course of our study patients, recognising the present follow-up time of five years for the vast majority of the cases, which would allow robust outcome analysis.
Similar(6)
However, both the prospectively collected and archived maternal plasma samples were processed using the same protocols and analysed prospectively.
Design Diagnostic accuracy validated against full karyotyping, using prospectively collected or archived maternal plasma samples.
The distribution of the false negative and true positive cases among the prospectively collected and archived samples was not statistically significant (χ test, P=0.258).
We recruited 576 pregnant women prospectively and retrieved archived maternal plasma samples from 248 women, which amounted to a total of 824 pregnancies (fig 1).
We extracted all data from our prospectively maintained archive of publicly accessible health statistics, named the Globally Accumulated health Indicator Archive (GAIA).
Proposals submitted for funding involved several different types of research methods, e.g., analysis of prospectively obtained biological specimens, qualitative research, analysis of archived data, and receipt of previously collected de-identified biological specimens.
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