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A prospective validation study is being undertaken to validate our findings and test the clinical utility of this biomarker for altering clinical practice.
Design: prospective validation study.
Design: Retrospective and prospective validation study.
This prospective validation study was conducted in patients undergoing pulmonary artery catheterisation during intensive care admission.
A large-scale prospective validation study will be needed to confirm our results.
Patients and methods: The prospective validation study was performed from June 23rd to July 11th 2017.
Similar(23)
Larger prospective validation studies are required to prove our findings.
From a review of decades of intensive biomarker research and prospective validation studies, it becomes clear that only a limited number of biomarkers can be used to provide reliable documentation of excessive exposure to environmental mutagenic agents, expression of detrimental biological effects from the exposure and increased risk for cancer.
Future prospective validation studies should be performed across multiple centers.
Several studies have derived thresholds that could be utilised in prospective validation studies.
The large-scale prospective validation studies are required in order to confirm our present findings.
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