Patients with BE and GERD were selected from an ongoing prospective tissue and serum repository at the Veterans Affairs Medical Center, Kansas City, MO, USA (clinical trials #NCT00574327).
The TR-DGU is a repository for prospective, standardised and anonymous documentation of data on severely injured patients requiring ICU treatment [ 6].
Consecutive patients presenting with ALTR from two major hip implant classes (N = 54 patients with Dual-Modular Neck implant; N = 14 patients with Metal-on-Metal implant) were identified from our prospective Osteolysis Tissue Database and Repository.
This study raised several important IRB issues that should be clarified by development of community consensus including: The manner in which undefined prospective research involving data and tissue repositories will be consented and handled.
We have demonstrated the feasibility of checking source clinical data for error, and the possibility of attaining high quality data using electronic data feeds for both prospective and retrospective parts of our data repository.
High-quality pathology data can be obtained for both prospective and retrospective parts of our data repository and the electronic checking of source pathology data for error is feasible.
Despite these limitations, the MUST study provides the largest repository of morphological data obtained from a prospective uveitis clinical trial to date, allowing improved correlation of baseline and follow-up findings with other outcome measures such as visual acuity and uveitis control.
The Cleveland Clinic GeneBank study is a large, prospective, cohort study that established a well-characterized clinical repository with clinical data and longitudinal outcomes from consenting subjects undergoing elective diagnostic coronary angiography from 2001 to 2006.
The development of new prevention strategies, leading to the promotion of health, requires access to and use of searchable repositories of biomedical data from population-based, prospective health surveys.
This study has added to our knowledge of accuracy of medication repositories by quantifying discrepancies in a large, prospective study of patients whom are typically at risk for medication errors.
