Further evidence as to the importance of the expression of key proteins in the Bcl-2 family comes from a prospective, randomized, radiation dose escalation trial that treated 305 men with localized prostate cancer with either 70 or 78 Gy.
After prospective measurement of radiation exposure during pediatric ureteroscopy for urolithiasis, we identified targets for intervention.
208 The EORTC and the Radiation Therapy Oncology Group (RTOG) are conducting a randomized prospective trial comparing fractionated radiation therapy alone, to 1) radiation followed by adjuvant temozolomide, to 2) concurrent chemoradiation without subsequent adjuvant therapy, and to 3) the regimen of concurrent chemoradiation followed by adjuvant chemotherapy that is the standard treatment for GBM.
Despite the long history of radiation use, prospective trials in the United States and Europe have been unable to demonstrate a survival benefit with adjuvant radiotherapy compared with observation.
The prospective study demonstrated that radiation therapy is a quick and efficient treatment of bone metastasis pain.
Jones et al. [ 30] described GI/pelvic grade I toxicity in 34% and grade II in 47% with no grade III side effects in their prospective trial on preoperative radiation.
Two prospective randomized trials comparing external beam radiation alone to radiation therapy plus alkylator-based adjuvant or neoadjuvant chemotherapy were initially reported as showing no survival benefit with the addition of chemotherapy.
The establishment of a mouse model is of great importance, as the availability of diverse immune-deficient mouse models could deliver more insight into immunological processes of radiation nephropathy in prospective studies.
To compare image quality, diagnostic accuracy and radiation dose of prospective and retrospective electrocardiogram (ECG) gated dual source computed tomography (DSCT) for the evaluation of the coronary stent, using conventional coronary angiography (CA) as a standard reference.
