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Focal brain metabolic effects detected by proton magnetic resonance spectroscopy (MRS) in obsessive-compulsive disorder (OCD) represent prospective indices of clinical status and guides to treatment design.
Prospective indices such as the Atlanta Classification [ 56], Ranson's criteria [ 57], or APACHE-II score [ 58] were used only in two RCTs [ 47, 49].
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An extension of the follow-up of the patients evaluated in this study is in progress in order to further assess the power of A-TTE and DSE in providing an early prospective index of silent SHI progression and a reliable prognostic score in SSc.
However, the graphical meta-analysis combined with effect size model fitting has several advantages over the count and traditional method: it makes obvious many fundamental problems with primary data including ceiling effects and yields unbiased estimate of effect size largely unaffected by widespread ceiling effects and low reliability of prospective memory indices.
The index prospective study was approved by the Johns Hopkins Medicine Institutional Review Board.
When based on prospective recordings the index may precisely and in a comparable manner reflect total headache burden.
In the index, prospective, observational study of patients with non-infectious vasculitis, the first, to our knowledge, to evaluate systematically and prospectively the role of ultra-wide-field imaging in retinal vasculitis, our results suggest that ultra-wide-field imaging may alter management decisions compared to standard-of-care imaging and clinical examination.
Moreover, asymptomatic infections are not detected in routine surveillance and can only be captured in the context of prospective cohort or index cluster studies [ 17].
Baseline tumor status with prospective identification of index lesions that were followed over the course of the study, was assessed using computed tomography (CT) studies of the chest, abdominal, and pelvis as well as determination of serum tumor-marker levels (carcinoembryonic antigen and carbohydrate antigen 19 9).
Accordingly, the majority of indices of prospective memory proper used in previous research suffer from low reliability due to binary outcome measurement (but see [12], [16] for examples of highly reliable continuous indices of prospective memory proper).
Consistent with these definitions, researchers have used performance on a wide variety of tasks as indices of prospective memory.
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