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We performed a population-based incident case-referent study based on a prospective incidence register entitled the Swedish National Childhood Celiac Disease Register [ 8, 9].
Further investigation through a prospective incidence cohort is warranted.
Firstly, it was a cross sectional study relying on past exposure, rather than a prospective incidence study.
First, by definition, cross-sectional and prospective incidence rates are estimated at different time points (over some time prior to baseline and during the months following baseline, respectively).
Specifically, the small sample size, along with other study design features, prohibited the use of more robust statistical methods for comparing the cross-sectional and prospective incidence rates, such as equivalence tests[33], and may have also led to reduced precision around the assay FRR estimates[9].
The study measures historical occurrence rather than prospective incidence.
Similar(40)
A prospective, incidence-based study design was employed [ 19, 20].
42 There were no prospective incidences available for adult/senior populations.
Retrospective and prospective fall incidence in ActiFE-Ulm did not differ.The retrospectively assessed incidence of 'any fall' among persons 65- < 80 years were significantly lower in DEGS1 than ActiFE-Ulm (women: 25.7% (22.4-29.2) versus 37.4% (34.8-39.9); men: 16.3% (13.6-19.3) versus 28.9% (26.6-31.1).
Twenty-five years of prospective nationwide incidence registration demonstrates a clear shift to younger age at onset rather than a uniform increase in incidence rates across all age-groups.
Eligible volunteers were selected from a rural general population cohort enrolled into prospective HIV incidence studies in preparation for HIV vaccine trials.
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