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We believe that in this study these errors are randomised between the retrospective and prospective data analysis, and hence do not contribute to errors in data analysis.
Data collection was prospective, data analysis was retrospective, and use of the data was approved by the hospital Institutional Review Board.
For the retrospective data, 10 process (these include the 8 indicators found to be statistically significant in prospective data analysis) indicators had statistically significant differences with magnitude of effects varying from 10%to42%2%.
In the prospective data analysis, definite radiographic progression was found significantly more often in VEs with MRI-proven inflammation at BL (10/153 VEs, 6.5%, 95% confidence interval [CI] 3.6% to 11.6%) than in VEs without BL inflammation in MRI (16/769 VEs, 2.1%, 95%CI1.3%to3.4 3.4%) (P = 0.006, odds ratio [OR] 3.3, 95% CI 1.5 to 7.4).
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Since 2010, all patients, who underwent ACL reconstruction using either hamstring or quadriceps tendon graft were enrolled in a prospective data base analysis and defined follow-up evaluations after approval before the beginning of treatment.
A prospective database data analysis.
Data collection was prospective and data analysis was retrospective and approved by the Sequoia Hospital Institutional Review Board.
In conclusion, in this large prospective cohort data analysis, we have confirmed that low birthweight children have a moderate associated risk of wheezing disorders whereas high birthweight children have a non-significant reduced risk.
The authors confused prospective data collecting and retrospective data analysis.
If a large patient cohort is available for meaningful data analysis, a prospective randomized trial should be started in the future.
We are aware that our study is only a retrospective data analysis and prospective studies should be conducted in order to evaluate policy on EBL procedures.
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