Exact(2)
Limitations: No formal, prospective comparison with other methodologies or indication of desired accuracy.
There are many possible applications of the SPPB as a standardized, objective measure for understanding physical function in older adults with MS. One application involves prospective comparison with other samples of older adults for understanding the effect of aging in the context of MS on physical function.
Similar(58)
The PARAGON-HF (Prospective Comparison of ARNI with ARB Global Outcomes in HF With Preserved Ejection Fraction) trial is designed to determine the efficacy and safety of the angiotensin receptor neprilysin inhibitor sacubitril/valsartan compared with valsartan in patients with chronic heart failure and preserved ejection fraction (HFpEF).
The prospectively designed phase III PARALLEL-HF (Prospective comparison of ARNI with ACE inhibitor to determine the noveL beneficiaL trEatment vaLue in Japanese Heart Failure patients) study aims to assess the clinical efficacy and safety of LCZ696 in Japanese HFrEF patients, and show similar improvements in clinical outcomes as the PARADIGM-HF study enabling the registration of LCZ696 in Japan.
The study design is a prospective comparison of MRI with classical pressure augmented colostography/fistulography in anorectal malformation patients, using final operative results as the reference gold standard.
Although no prospective comparison was made with a cohort without HIV, similarities exist in the microbiology of infections and incidence of organ dysfunctions with the non-HIV/AIDS population reported in the literature [ 20, 48, 49].
LCZ696 is the first ARNI to be tested in patients, and here we describe the design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortalilty and morbidity in Heart Failure trial (PARADIGM-HF).
3, 7, 9 The Prospective comparison of ARNi with ACEi to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF) is testing the hypothesis that LCZ696 200 mg b.i.d is superior to enalapril 10 mg bid is reducing mortality and morbidity in patients with heart failure and reduced ejection fraction (HF-REF).
Patients with chronic HF, NYHA class II IV symptoms, an elevated plasma BNP or NT-proBNP level, and an LVEF of ≤40% were enrolled in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortailty and morbidity in Heart Failure trial (PARADIGM-HF).
In a prospective comparison of 58 patients with suspected renovascular hypertension, Rountas et al. [99] found that CE-MRA has a slightly lower sensitivity than CTA for the detection of renal artery stenosis or fibromuscular dysplasia, 90% versus 94% respectively; this is likely due to the lower spatial resolution of MRI compared with CT.
In a prospective comparison of Griggs' technique with standard ST, Griggs et al. [ 38] reported rates of 3.9%and8.1%1%, respectively, for perioperative complications.
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