The novel longevity locus we identified was tested for association with prospective (cause-specific) mortality in a meta-analysis of 11 European cohorts and examined for association with various metabolic traits that may explain the mechanism by which the locus contributes to survival to high ages.
Previously characterized admission serum samples (total n = 100) were used that were collected from febrile illness patients enrolled in ethically and fully Institutional Review Board-approved prospective "causes-of-fever" studies performed in Udon Thani in northeastern Thailand (2000 and 2001; n = 85) and Kathmandu, Nepal (2008 to 2011; n = 15) (8, 9).
The use of small model organisms with short generation times such as C. elegans, S. cerevisiae and D. melanogaster, has facilitated testing of hypotheses to illuminate a prospective cellular cause of protein-misfolding diseases like HD, PD, Amyotrophic Lateral Sclerosis (ALS) and AD or neuroprotective mechanisms against neurodegeneration [ 3, 4].
Cause of death was determined by transplant committee multidisciplinary consensus in a prospective fashion when cause of death was ascertainable.
The judge, Joseph E. Gary, refused to allow the defense to challenge for cause prospective jurors who had already formed a settled opinion of the defendants' guilt.
Mr. Naider said he did not yet know whether Judge Batts's decision would cause prospective advertising clients to think twice about doing business with him.
Otherwise the financing of the large prospective deficits will cause a competition between government and business for available funds, which the government will win, thus driving up interest rates.
Unlike the prospective solutions, the cause of the crisis was very simple.
Americans collectively have more than $1.2 trillion in student loan debt, an amount that may cause prospective students to wonder whether college is worth the cost.
Too often, artists shy away from questions of care, because they themselves may not know much about the materials they are using and how their pieces weather over time (and what, if anything, to do about it) and because they worry that such talk might cause prospective buyers to back out of a purchase.
