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It is crazy that the prospective benefit for these cuts is the avoidance of revenue reforms that would ask some to pay a little more and others simply to pay what they are supposed to be paying already.
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For Islamic State, the prospective benefits of Western troops engaging them on the ground are obvious.
The prospective benefits of employing multiple diverse sensors outweigh the potential limitations.
First, investigators with their IRBs determine whether the balance of research risks and prospective benefits are ethically justified for the population to be recruited.
The prospective health benefits for patients with stages 1 3 of invasive cancer, compared to those with more advanced stages, should thus be clearly explained.
Prior prospective studies have shown mixed benefit for extending survival in relapsed FL.
There is no prospective data regarding a survival benefit for patients with metastatic prostate cancer undergoing treatment of the primary tumor.
However, in clinical practice not all data points from these scores are readily available or calculable, and no robust prospective studies have shown any benefit for withholding anticoagulation on the basis of a high bleeding score.
The sole prospective randomised trial to report survival benefit for neoadjuvant combination chemotherapy and radiation therapy compared with surgery alone was undertaken at this centre between 1990 and 1995 (Walsh et al, 1996).
However, a recent prospective randomised phase III study (GBG26) showed benefit for trastuzumab continuation alongside capecitabine compared with capecitabine alone.
The results of the randomized AZA-001 trial make azacitidine the first specific therapy to show a definite survival benefit for MDS patients in a prospective randomized study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com