Cornell and VitaScan will together develop a medium-scale manufacturing and packaging process to optimize its proprietary procedure and create reliable tests for validation studies.
RNA isolation after dissection was performed according to a proprietary procedure (Response Genetics Inc., US patent no. 6248535).
RNA was isolated from these using a novel, proprietary procedure (Response Genetics, Los Angels, CA United Statess Patent Number 6,248,535).
RNA was isolated from the macrodissected tumour tissue specimens in accordance with a proprietary procedure (European patent number EP1945764-B1).
After hematoxylin-eosin staining, RNA was isolated in accordance with a proprietary procedure as we published before [ 21].
RNA extraction was performed according to a proprietary procedure (US patent number 6,248,535) (Lord et al, 2000; Kornmann et al, 2003).
RRM1 and RRM2 gene expression analysis was performed in RNA isolated from tumour tissue specimens after laser capture microdissection (Palm, Oberlensheim, Germany), according to a proprietary procedure (patent pending EP05077417.3) of Pangaea Biotech, SA.
All other sections were selectively dissected by laser captured microdissection (P.A.L.M. microsystem, Leica, Wetzlar, Germany) according to the standard procedure [ 22] RNA isolation from OCT-embedded specimens was done according to a proprietary procedure of Response Genetics, Inc. (US patent number 6,248,535) [ 23].
We show that the control data for both platforms, after proprietary manipulation procedures, are well behaved using some statistical measures.
