To overcome this problem, different ex vivo expansion strategies have been proposed to amplify the numbers of these cells so that they can be employed more efficiently in the clinic.
Dvl proteins localize to dynamic, cytoplasmic and plasma membrane-associated aggregates that have been proposed to amplify Wnt/β-catenin signaling [24].
Membrane PR3 expressed on apoptotic neutrophils has been proposed to amplify inflammation and promote autoimmunity by affecting the anti-inflammatory reprogramming of macrophages [ 46].
Although amylin has been proposed to amplify leptin signaling in the hypothalamus, thereby synergistically effecting weight and fat loss in animal models (6), the molecular mechanisms underlying these effects remain to be fully clarified.
However, Ca2+ release from the lysosomes have been proposed to be amplified by Ca2+ release from the ER by a process of Ca2+-induced Ca2+ release, and may therefore also modulate proximal steps in the autophagy pathway., Moreover, recent work of different groups highlighted the possibility of complex, bi-directional functional interactions between lysosomal and ER Ca2+.
proposing to overthrow democracy.
In this work, a primary measuring instrument was firstly proposed and designed to amplify vibration signal caused by sand impacting so that it can be much easier to receive for the sensor.
Simulations and experimental results show that the proposed method is effective to amplify the single fault signatures and calculate fault indicator at variable speed.
High-Z nanoagents, such as metallic (gold, platinum) and oxide (hafnium, gadolinium) nanoparticles (NPs), have been proposed as potential nanodrugs to amplify radiation effects.
Introduction: "Therefore, cortical circuits are proposed to contribute to and amplify SSA in A1… We found that both types of interneurons contribute to SSA in the cortex, with PVs providing constant inhibition, and SOMs increasing their effect with repeated tones".
To overcome these limitations, the addition of NREs to the tumour is proposed as a challenging strategy to amplify the effect of ion radiation locally and thus reduce the total dose to the patient.
