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To circumvent this, Le Doussal and co-workers proposed the Affinity Enhancement System or AES (Le Doussal et al. 1990).
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Recently, Haidar et al. proposed that the affinity of immunoglobulin interactions is inversely proportional to the backbone flexibility of their corresponding CDR3, while it was independent of the flexibility of CDR1 and CDR2 [35].
(2007) have proposed that the affinity of the MTBD for MT is sensitive to the angle between the stalk and the MT. We favor this model, because the low stalk-MT angle demanded for larger steps would disfavor MT reattachment, thereby biasing the motor toward smaller steps.
Therefore, Bolstad et al. [ 9] proposed the GCRMA to adjust the affinity among nucleotides because of different binding strengths between GC and AT rather than the RMA provided by the Affymetrix Console, as the latter is designed for processing Affymetrix chips.
Others proposed the utilization of lexical affinities to automatically refine queries [13], and the usage of both the text surrounding the query terms in the search results and the text surrounding the query term in the document being read [16].
Because the effect of some ubiquinone analogs depends on the cell line, we propose that the affinity of these sites for one particular quinone, as well as the secondary changes in the PTP Ca2+ binding affinity, may change according to the cell line.
Positive estimations of ΔS° proposed great affinity of the metal ion toward the adsorbent and expanded arbitrariness at the solid-solution interface amid the obsession of the metal ion on the active site of the adsorbent.
We also demonstrated that the newly proposed VEGF121-NRP1 affinity has a negligible effect on the VEGF signaling profiles (Fig. 4D,E).
A computational model was proposed to evaluate the affinity and selectivity of 2- 3,4-dimethoxyphenyl)ethylamine (homoveratrylamine) imprinted polymers.
The complex was suggested to illustrate a presumed transient selenenylsulfide-linked intermediate that would form during normal catalysis with native enzymes, whereby Trp114 was proposed to increase the affinity of TrxR1 for Trx1 as it resulted in a lower K m value when Trp114 was present.
In addition, the diversity amongst the individuals is controlled by means of the proposed Affinity Based Replacement Strategy (ABRS) mechanism.
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