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In the case of COA3-null mutant, only HSP26 upregulation was in common with the proposed CORE pathway (Fig. 3c).
The proposed CORE pathway encompasses activation of protein conformational maintenance machineries, antioxidant enzymes, and metabolic changes simultaneously in the cytosol, mitochondria, and the ER.
CIT1 and IDH1 experienced an increase in the expression level, unlike in the context of the proposed CORE pathway (Fig. 3c).
A letter (or email) is required from each proposed core member indicating his or her interest in the program as an Appendix.
Results show that the proposed core performs well in terms of the neutron multiplication factor and reactivity coefficients.
Their proposed core consisted of the five countries judged ready for currency union: France, Germany and the Benelux trio.Today Mr Lamers concedes that his old core would no longer work, not least because Benelux has broken down.
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The current study proposed core-scale numerical investigation models for the complex multiphase dissociation flows of methane hydrate inside porous media, which is a continuation and an extension of previous numerical investigations.
The calculation results show that the proposed core-uprated design with thermal power of 1200 MWt shows preferable characteristics, such as low power peaking of around 1.43, negative reactivity coefficients, and relatively high MDNBR of 3.454.
It was found that as opposed to the reference design, the new proposed cores are inherently stable as far as temperature reactivity feedback is concerned.
However, in the case of proposed cores, the reactivity added would be about 10% of that added in the reference core for loss of a given fraction of coolant.
Moreover, as opposed to the NRX/CIR core, the shut-off rods, under the one stuck rod criterion, can shutdown and maintain the proposed cores subcritical in the accidental conditions.
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