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His method of tabulating data on animal groups in geographic zones highlighted the discontinuities; and his appreciation of evolution allowed him to propose rational explanations, which had not been done before.
We believe that by proposing a site of initiation for the final common pathway, future research may lead to an unifying model including non-substance dependent addictions to gain further mechanistic insight, and propose rational therapies.
Finally, based on the topology and membership of the driver-networks, one could propose rational combinatorial therapies, which might not be possible by only analysing a list of driver genes.
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In each case he details what is known, separates fact from fiction and proposes rational strategies to alleviate the danger.
Comparison of the proposed rational cubic FIF over some existing schemes: When all the scaling factors are zero, the proposed rational cubic FIF reduces to the classical rational cubic interpolant [20], see Remark 1, Section 3.
In the proposed rational cubic IFS, we assume q i ( i = 1, 2, …, n − 1 ) are the rational functions with 3-shape parameters, whose denominators are preassigned quadratics.
When all the scaling factors are zero, the proposed rational cubic FIF reduces to the classical rational cubic interpolant [20], see Remark 1, Section 3.
The classical interpolants [15, 23] are suitable only for monotonicity interpolation whereas the proposed rational cubic FIF is suitable for both monotonicity and positivity interpolation.
To facilitate accurate but conservative design of cellular beams for resistance against lateral torsional buckling (LTB), this study proposes rational design guidelines based on General method of EC3.
The proposed rational approach expresses fire resistance in terms of conventional structural and material design parameters, and thus facilitates easy evaluation of fire resistance.
Moreover, the local response of each component and its effect on the global behavior of the element can be obtained which is useful for proposing rational design relations.
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