It is not known what causes this typically noninvasive organism to penetrate mucosal surfaces, though some authors have proposed an alteration in the pharyngeal mucosa by a viral or bacterial pharyngitis might play a role.
This mechanism proposes an alteration of the strength of intermolecular interaction forces that in effect change the mean free path of the nanoparticles and hence augmenting the heat transfer of molecules [48].
In contrast, under acidic conditions, we propose that an alteration in the protonation state of H150 triggers the re-arrangement of the linker region connecting α4 with α5 such that the linker is now part of α5.
We propose that an alteration of Met signalling, such as HGF/Met overexpression, giving a message of nutrition or oxygen restriction, could mimic the molecular effect of these environmental cues.
It has been proposed that an alteration in the development and/or composition of the microbiota may disturb the relationship between microbes and the immune system.
They propose a grandiose, entirely pointless alteration of a public place, then advance their plan in the face of a predictable public and bureaucratic resistance, which gradually comes to seem mean-spirited and foolish for want of a reasonable argument against them.
It is concluded that, for filled elastomers, the weak physical filler chain interactions are the main broken links during deformation; hence, their morphology is precisely noticed to propose a physically-motivated network alteration theory for the Mullins effect by determining the evolution of the network parameters.
Based on our findings, we propose a model whereby the alteration of NF-κB activity at the early stages of infection with pathological prion protein leads to neuronal cell death mediated by mitochondrial apoptosis.
In summary, we propose a model whereby pathological alterations in cardiac lipid utilization activate a distal PKC-dependent MAPK signaling cascade that promotes excessive hepatic PEPCK expression and gluconeogenesis in HCM mice, in a sexually dimorphic manner (Fig S20).
