This feature is in agreement with our previous proposal that sequence specificity is conserved across E2C domains from alpha papillomaviruses (18).
Our data support the proposal that sequencing of intron 3 of PLP1 should be included in standard diagnostic procedures because of the importance of this region for controlling PLP1/DM20 alternative splicing.
Authors' response: Although we have not included with our proposal a possible sequence for the first anticodon loop, it seems reasonable to believe that the CCA sequence has always been in its current location, with (N CC in the anticodon position.
In our proposal, in each sequence of future states, the decision-making algorithm looks for the relevant changes defined in the system (such as a device running out of battery charge).
For a given reference sequence, proposal orthologs are conceptualized as nodes in a graph, connected with edges weighted according to the pairwise similarity between sequences.
While rapid prediction approach is based on utterances, that is specific linguistic forms, i.e. words, phrases and sentences, our present proposal specifies action sequence structures in terms of intentional speech acts, each of which can be realised with a range of different utterances (see " Introduction" section).
This proposal mirrors the sequence of events we infer for kinesin, where the magnitude of the peptide backbone distortion appears to be greatest in the ATP state, less for the ADP states, and least of all for the no-nucleotide conformation.
The adjective "sticky" highlights the ability of the proposed schemes to generate a sequence of proposal densities that progressively "stick" to the target.
This lever rule facilitates the proposal of alternative sequences of reactive distillation systems by allowing us to visualize how material balance constraints move as a function of reaction "turnover".
The interpretation of each dta file resulted in several peptide sequence proposals, and all candidate sequences were assembled into a single query for MS BLAST search [82] as described in [83], [84].
