Traditionally, mathematical modelling of the spread of airborne infectious diseases used age-mixing matrices that were chosen for mathematical convenience, such as proportionate mixing and so-called "who acquires infection from whom" (WAIFW) matrices [12].
The assumption of proportionate mixing in a large population ignores the clustering of individuals at high risk.
We assume a proportionate mixing law for the incidence function of FIV between males, which is more appropriate in social species [22], [23].
The self reported social contact data derived from such surveys have been shown to better predict the observed patterns of respiratory infections than other representations of contact probabilities, such as homogenous or proportionate mixing [12], [14], [15], [16].
If the cost of disease is very low there is little incentive to avoid it, and disease dynamics will be those associated with proportionate mixing.
The fully assortative and fully proportionate mixing matrices between the six age-groups were also generated and later used as two extremes in the transmission model.
Matrices for VT and NVT were calculated assuming fully assortative (βa) and proportionate (βp) mixing between the six age groups.
The authors rightfully say "We do not know how trans-SNARE interactions lead to this dequenching, but it is not symmetric, as expected for true lipid mixing, and is not proportionate to the content mixing for each reaction condition; thus, it cannot be relied on as a faithful reporter of fusion".. What is the origin of the asymmetric lipid dye transfer?
We do not know how trans-SNARE interactions lead to this dequenching, but it is not symmetric, as expected for true lipid mixing, and is not proportionate to the content mixing for each reaction condition; thus, it cannot be relied on as a faithful reporter of fusion.
