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Exact(4)
A ΔZV/ΔZQ of 1 does not imply that the components have the same magnitude change, but rather that the proportion of ventilation and perfusion are matched, that is, ΔZVmax/ΔZQmax OR ΔZVmin/ΔZQmin.
At a given respiratory rate, lung units with a shorter time constant receive a greater proportion of ventilation than do lung units with a relatively long time constant, and may contribute to regional overinflation [ 34], which is reflected in dynamic indices of overdistension.
In this way the ΔZV\ΔZQ is not like a traditional VQ ratio but rather is a ratio of maximal ventilation to maximal perfusion, with a value of 1 occurring in a region in which the proportion of ventilation and perfusion are matched, that is, ΔZVmax/ΔZQmax OR ΔZVmin/ΔZQmin.
At baseline conditions, a parallel distribution of ZV and ZQ was observed, with the greatest proportion of ventilation and perfusion appearing in ROI 2 followed by ROI 3 and then ROI 1, while only a minor, although equal, fraction was observed in ROI 4. Binfl decreased the proportion of ZQ distributed to ROI 2 in both the left and right lung and increased the proportional ZQ in the left ROI 1.
Similar(56)
We calculated that we would require a sample size of 520 patients to show a relative hazard of 0.70 for two year survival comparing two equally sized groups of patients (those receiving greater than compared with less than the median proportion of eligible ventilation days using lung protective ventilation) with an α of 0.05 and statistical power of more than 85%.
The proportion of minute ventilation due to spontaneous breathing during APRV with spontaneous breathing could not be measured directly, because the spontaneous breathing activity partially coincides with mechanical breaths.
Interestingly, our results were obtained in a population with a high proportion of mechanical ventilation (90%%).
In these circumstances V ˙ / Q ˙ is high and a proportion of the ventilation can be considered as "wasted".
However, this linear correlation is crucially dependent on electrode position, conformational changes of the chest wall and diaphragm and the proportion of tidal ventilation distributed in the lung areas falling inside and outside the EIT image during tidal breathing [ 58].
For testing the time course of mortality, mortality in patients requiring mechanical ventilation, and the proportion of patients requiring ventilation assistance, we evaluated the linear correlation of those variables with time by using the least squares linear regression method.
When invasive ventilation was used, the proportion of days on ventilation during which the patient received a positive end-expiratory pressure of greater than 5 cm H2O was lower for HIV-positive cases (70%[3%to100%00%]) compared with HIV-negative patients (90%[70%to100%00%]; p = 0.04).
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