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Routine diagnosis of Human T Lymphotropic virus (HTLV) infection is primarily serologically based; however the proportion of unresolved and indeterminate Western blot results range from 0.02%to50%0% in endemic areas.
We assumed the proportion of unresolved ASCUS+ samples to remain the same over time.
This indicates that enforcement of a higher-stringency limit on acceptable confidence probability scores generally leads to an increased proportion of unresolved genotypes per dataset.
* including the outgroup S. nicolai The proportion of unresolved and partially resolved quartets is shown for phylogenies based both on single gene fragments, and on the combined data.
Briefly, this analysis enables to estimate the suitability for phylogenetic reconstruction of a data set from the proportion of unresolved quartets in a maximum likelihood analysis.
Uncertainties remain due to the high proportion of non-categorized repeats in the genomes of Lml, Lbb, Lbc and Lbt (19.2-48.8%) and higher proportion of unresolved nucleotides in the assemblies compared to the reference Lmb v23.1.3 (Table 1).
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Finally, in the context of diagnostic virology laboratories, our study shows that standard extraction and amplification techniques used for the molecular diagnosis of human pathogens led to a significant proportion of 'unresolved' results, which cannot be identified if an internal control is not used.
The proportion of patients with unresolved diarrhea after 120 hours was similar in both treatment groups.
The proportion of patients with unresolved diarrhea after 120 hours was similar in both treatment groups (table 3).
These included time taken for prespecified proportions (such as 50%) of children's symptoms to have resolved, the study population, proportion of children with unresolved symptoms at follow-up, or mean or median duration of symptoms.
Overall, we found a low risk of individual children not being cured 57% at one month, decreasing by a further 60% at three months and 60% at nine months (proportion of those remaining unresolved throughout 0.18, 0.13 to 0.26) (fig 2).
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