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This can now be rationalized by the observation that very high DUB activity markedly reduces the proportion of substrates that acquire a polyubiquitin degradation signal with each ligase encounter, and the length of time that signal persists.
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The ldh mdh mutant fermented the same proportion of substrate but produced significantly less acetate and more than twice the concentration of ethanol.
Xylanases have also been suggested to increase the proportion of substrate available for productive cellulase interaction due to their unproductive binding to sites on lignin [ 36, 37].
This feature is characterized by the proportion of substrate enzyme pairs separated by the shortest path length h, and it is defined as follows:.
This feature is characterized by the proportion of substrate enzymes separated by the shortest path length h from the central (source) node o, and it is defined as follows:, where d o, x) is the shortest path length from the source node o to node x.
We found significantly greater proportions of substrate and NPV over non-forest compared to forest areas that enabled identification of forest cover across dry season images.
Using a linear spectral mixture analysis (LSMA) approach with Landsat 5 8 data, we examined the hypothesis that higher proportions of substrate and non-photosynthetic vegetation (NPV) at non-forest regions distinguished them from forest cover against seasonally variable land cover conditions.
This set of proteins includes a substantial proportion of known substrates from previous in vivo and in vitro studies, as well as substrates that were confirmed as in vivo phosphorylation sites by mass spectrometry.
Using the hypergeometric distribution analysis, we calculated the probability that the proportion of SUMO substrates mapped to a given category could occur by random chance, given the fraction of all fly proteins that map to that category (Table S4, S5).
Secondly, since the protein microarrays are produced with recombinant human proteins expressed in Sf9 insect cells a proportion of these substrates could be misfolded, possibly precluding their modification or promoting their artificial modification.
In all, about three-quarters (78%) of PTCs were located more than 50 nucleotides upstream of the last exon-exon junction, and thus predicted to produce a marked proportion of NMD substrates [ 5].
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