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IL-1 enhances the proportion of responding CD4 T cells that differentiate into Th17 cells and increases the proportion of responding CD8 cells that express granzyme B. Of a wide range of cytokines tested, only IL-1α and IL-1β mediate this function.
The proportion of responding subjects was quite low and probably not totally representative of the whole population of migraine sufferers since most participants were severe migraine sufferers and already enrolled in the healthcare system.
A larger proportion of responding neurons was concentrated in the posterior areas of the GP (Fig. 2).
Thus, although we did not (and could not) test a continuum of sounds from one category to another, the proportion of responding sites and the magnitude of responses clearly differed between functional classes of songs and less within them.
This was associated with a five fold increase in the proportion of responding cells, such that 14 days after the induction all EBs were functionally responsive to KCl-induced depolarization of the membrane.
This proportion of responding neonates was significantly higher than for all reference stimuli [water: 21%; sebum: 21%; human milk: 26%; cow's milk: 26%; formula milk: 16%; vanillin: 5%; and familiar milk: 16%; Friedman's analysis of variance (ANOVA), F 19,7) = 19.13; p<0.01; all pair comparisons (using Fisher's χ2 test) between AG secretion and all other stimuli, p<0.05].
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However, within each level of reinforcement, the proportions of responding in SD as a function cumulative SΔ exposure were equivalent, regardless of the number of reinforcers earned in SD, suggesting that extinction is the "hallmark" of discrimination.
End points included proportion of patients responding to ≥6/12 pneumococcal polysaccharide vaccine (PPV23) serotypes (primary) and proportions responding to tetanus toxoid vaccine (TTV; secondary) at week 8. 91 patients were randomised.
After 6 weeks of treatment, the proportion of patients responding to OROS MPH was significantly higher than the proportion of patients responding to atomoxetine (56 vs. 45% respectively; P = 0.02).
The OR is equivalent to a difference between two paired proportions of 0.250, which occurs when the proportion of patients responding to almotriptan and not to placebo is 0.500 and the proportion of patients responding to placebo and not to almotriptan is 0.250.
Amongst children, selection bias was less of a problem because of the higher proportion of persons responding, though the level of activity amongst responders may still be higher than non-responders.
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