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In general, a proportion of prognostic information is lost through grouping, which should be reflected in the estimates of the measures.
Furthermore, because of inconsistencies in the design and analysis of method evaluation studies, a high proportion of prognostic studies were presented with poor methodology which resulted in the presentation of conflicting interpretation of variability of the measures.
In this situation, gene sets containing many genes are likely to perform better than gene sets with a small number of genes because a greater proportion of prognostic genes are consistently present across all platforms.
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Our results demonstrate that the LML subset has a significantly higher proportion of good prognostic mutations than poor prognostic mutations (p = 0.002), (Fig. 4a).
Proportion of significantly prognostic genes across different comparison groups.
This study incorporated more patients who were classified as low-risk PTD by the revised classification, resulting in a higher proportion of higher prognostic risk scores, and thus an increased MTX resistance rate.
Our objectives were to determine what proportion of patients think prognostic information is important, the reasons they give for (not) why they feel prognostic information is important, and to ascertain how often patients feel that their prognosis is discussed in the consultation.
The aim of this study was to pool data on the proportion and prognostic impact of sources of bleeding in patients requiring re-exploration after adult cardiac surgery.
Therefore, we evaluated the proportion and prognostic significance of promoter methylation of MGMT, ABCB1 and ABCG2 in 64 GBM patient samples using pyrosequencing technology.
The phase III trials that confirmed the benefit of sunitinib, bevacizumab + IFN, and pazaponib each enrolled a small proportion of patients with poor prognostic features.
Although there were significant differences in the proportion of many commonly used prognostic factors between screen-detected and non-screen-detected tumors, the frequency of lobular carcinoma was similar in both groups.
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