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Exact(8)
The TB patients were significantly older, with male predominance, and had higher proportion of prior TB history and underlying co-morbidity compared to the family contacts (Table 1).
Our study was designed to prove a 1-year survival of 30%, which is somewhat high considering the patients' general condition and proportion of prior exposure to chemotherapy.
Following previously used methods [13], the 'estimated CCU trend ' hypothesis was deemed most likely only if it achieved a higher frequency of fits (proportion of prior parameter sets that produced model fits) than the two alternative control CCU trend hypotheses.
In particular, a high proportion of prior brand use (β's ranging from 2.968 to 5.809, with P < 0.001 in both cases) as well as whether the patient is dispensed a prescription for the specific drug class for the first time (β = 2.752, P < 0.001) were found to be positively related with the probability of branded substitution.
In particular, the probability of generic substitution for a prescription was found to be significantly and positively related to the experience of the patient on the use of drugs of the same drug class but negatively related to the proportion of prior branded use in this drug class.
The fixed effects estimates indicate that the probability of generic substitution is negatively associated with a high proportion of prior brand use (β's varying from -3.210 to -5.952, with P < 0.001 in both cases; see Table 3) and receiving a prescription further beyond the patent expiry date (β = -0.011, P = 0.002).
Similar(52)
We found in this study that primary MDR-TB cases, primary DS-TB cases, and controls had similar proportions of prior exposure to TB cases, which were similar with findings of a study in Peru and another study in China.
We argue that the presence of a higher proportion of micronuclei prior to the Bragg peak at the higher radiation dose is the consequence of "overkill" at the physical Bragg peak location.
Studies in other populations have also found that QT prolongation is often present in a proportion of patients prior to the administration of droperidol.
The non-compliant group had a larger proportion of hospitalizations prior to the index dose than the compliant group (24.9% vs. 2.2% of RSV-related hospitalizations, respectively).
And fourth, the high proportion of deaths prior to presentation at a hospital and the pattern of bypassing district hospitals raise questions around the adequacy of first aid responses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com