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One potential application to ML-based predistors is dynamically setting the prediction threshold such that the proportion of predicted active residues matches the estimated prior distribution for the query protein.
To estimate the proportion of predicted genes in the genome, the number of gene predictions is expressed as a percentage of the total of number of genes both predicted and from UniGene.
We examined the sensitivity (the ability of the model to identify specific cases), specificity (the ability of the model to identify non-cases), and precision (the proportion of predicted cases that are correctly real cases) of model prediction for each time activity category.
The precision is the proportion of predicted CEMs that are actually true CEMs.
Thoroughness concerns the proportion of predicted real problems relative to the full set of real problems [35].
The other 71% of expressed sequences are either compensated (56%, with a large proportion of predicted genes and antisense transcripts) or highly variable among individuals (15%).
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The predicted and actual prognoses (SVR or non-SVR) of the VS patients were compared to obtain the following three measures of prognosis prediction performance: (1) accuracy (proportion of correctly predicted prognoses), (2) sensitivity (proportion of correctly predicted non-SVR) and (3) specificity (proportion of correctly predicted SVR).
This predicted kinome is a relatively large proportion of all predicted protein coding genes, at 2%.
More importantly, functional testing in mouse transgenic assays has validated the predicted enhancer function of a large proportion of these predicted elements.
ePositive predictive value, proportion of patients predicted to have SWG who had substantial weight gain (estimated using leave-one-out cross validation).
fNegative predictive value, proportion of patients predicted not to have SWG who did not have substantial weight gain (estimated using leave-one-out cross validation).
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