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For prescriptions that were still active on the date of an event, the total consumed dose was reduced to reflect the proportion of pills expected to have been consumed by that date.
HAART adherence was assessed every month by pill count and expressed as the mean of the proportion of pills taken to pills that should have been taken, for each antiretroviral drug during the previous 30 days.
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Between fall 2012 and spring 2014, the proportion of pill users paying zero dollars out of pocket increased from 15%to67%7%, with similar trends for injectable, ring and IUD users.
We calculated the prevalence of malfunctioning EM systems (assumption 1), the prevalence of reported cap recording mismatches and non-adherence to the EM system (assumption 2), and the proportion of pill organizer users not participating (assumption 4).
At each visit, pills remaining in bottles were counted and the proportion of these pills to the dispensed pills during the previous visit was calculated based on the dose and the number of days dispensed.
Over this time period, the mean proportion of incorrect pills taken was only 2.3% incorrect pills, compared with a historic mean of 22% incorrect pill taking in this clinic population.
The mean proportion of incorrect pills taken during the intervention was 2.3% incorrect pills, compared with a historic mean of 22% incorrect pill taking in this clinic population.
We assessed compliance by pill count at each visit and analyzed it as proportion of expected pills used between baseline (first trimester) and end of follow-up (8 months' gestation).
The proportion of study pills taken was assessed at each follow-up visit throughout the CHARM trial.
The level of adherence was defined as the proportion of prescribed pills actually taken on time (i.e., within 1 hour of scheduled dose time) over a 4-day period.
The study ultimately concluded that since the percentage of women who incorrectly misdiagnosed themselves is similar to the proportion of actual pill users in the US who are contraindicated for use, the over the counter sale of birth control pills would likely be safe.
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