However, the collection is limited by the numerical aperture of the objective (NA) and the refractive index of the medium (RI), and scales the collected QD fluorescence by the proportion of the objective solid angle to the whole angle of the emission sphere.
In a behavioural economic study by Harbaugh et al. (2002), in which participants aged 5 64 years made a series of choices between a certain outcome and a gamble with equivalent EV, the proportion of unbiased, objective decisions increased with age.
I do get nervous if their pain is way out of proportion to objective findings.
Red flags emerge from different information, including inconsistencies between subjective and objective assessments: I do get nervous if their pain is way out of proportion to objective findings.
One physician said: " I also look to see if he's got legitimate reasons for pain, 'cause sometimes patients' pain is way out of proportion to objective findings, like radiographic findings" (Physician 2).
The primary end point of this study was overall survival and secondary endpoints were PFS, proportion of patients with objective response, duration of response, change in tumor size, 6-month PFS and safety [36].
Strobe 16: Please provide 95% confidence intervals for the estimated proportion of the primary objective.
The primary efficacy endpoint was investigator-assessed progression-free survival (PFS) at 9 months (defined as the proportion of patients without objective tumour progression (RECIST version 1.1) and alive 9 months after randomisation).
66, 67 However in the TALENT trial, although the proportion of patients with objective responses was similar for the erlotinib and placebo arm (31.5% vs 29.9%, respectively), the duration of the response (though not the median time to symptomatic progression) in the experimental arm with erlotinib was small but significantly greater (median 25.4 vs 23.9 weeks; HR 0.77; P = 0.045).
When the newborn shows highly compromised clinical conditions the physician will have to take into consideration the advisability of not starting or continuing extraordinary therapies, which would be out of proportion to the objective of the best interest of the little patient.
