Sentence examples for proportion of mutation from inspiring English sources

This suggests that BRCA screening policies based on family history only would miss a considerable proportion of mutation carriers.

Ongoing efforts by CIMBA aim to increase the proportion of mutation carriers diagnosed with breast cancer who also have available tumour pathology information.

Eligibility criteria for BRCA1 and BRCA2 mutation testing based on family history and age of onset will identify only a small proportion of mutation carriers.

Table 2 shows that the proportion of mutation carriers generally increased as the number of first-degree relatives with breast cancer increased.

The proportion of mutation events = [(NS + ID /L] × 100, where NS = the number of nucleotide substitutions, ID = the number of indels, L = the aligned sequence length.

A similar proportion of mutation positive vs. negative cases responded to selumetinib treatment, leading the authors to postulate that its activity may not depend on BRAF/KRAS mutational activation.

Comparing this value to the overall average rate gave an estimate of the minimum proportion of mutations that were disadvantageous.

c The smaller the mutational step relative to the curvature (i.e. distance from the optimum), the greater will be the proportion of mutations that are advantageous.

Patients with the mental illness, which affects about one in every 100 people, had a higher proportion of mutations known as copy number variations in the genes involved with exciting or inhibiting the synapses between brain cells, the researchers report.

However, irrespective of this limitation, it does appear that the proportion of mutations associated with T-cell pressure is higher in HIV (30 60%) than for HCV (31.8%).

As the population size increases so the level of neutral diversity increases, but at the same time the proportion of mutations that are effectively neutral decreases.