Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
Our results, of a low proportion of lethality in young genes, contrasts with a previous conclusion that young genes have a similar proportion of lethality as old genes [ 21], a result that might have been attributable to the off target effects of RNAi on duplicated genes, producing false positives for the essentiality of the young duplicated genes.
Similar(58)
In agreement with the high proportion of embryo lethality, all M2 families segregated for easily visible morphological mutations (data not shown).
To describe the dimension of lethality we henceforth use the term 'complete lethality' for 100% lethality in laboratory experiments.
Notably, this proportion of the orthologs displaying lethality (35%, [53/150]) was significantly different from the proportion of all knocked out genes associated with lethality in the MGI database (23% [1567/6812], p-value = 0.0006).
The proportion of young genes showing lethality (3.3%) was slightly lower than the genome wide value (8.9%, http://bristlescreen.imba.oeaw.ac.at/data_summary.php).php
On the other hand, when considering mortality, real differences in incidence may be attenuated, since lower participation rates in screening programmes have been reported in rural areas[ 32] and this translates as a lower number of in situ tumours and a higher proportion of more advanced stages with increased lethality[ 36].
In fact, the same proportion of ligated cecum between these two breeds of animals does not exactly have same consequence in terms of lethality.
Homozygous inactivation of Cux1 in mice causes perinatal lethality in a large proportion of animals due to delayed lung development and associated respiratory failure [ 28].
In addition, many lethal lines showed a high proportion of embryos that died prior to cuticularization, indicating early embryonic lethality.
There is a risk of lethality here," she said.
Each of these can also be upgraded to a second level of lethality.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com