Sentence examples for proportion of integration from inspiring English sources

In the LEDGF/p75 knockdowns (Figure 5, orange and yellow shading), the proportion of integration sites in genes was reduced, with the percent change significantly greater in the intensified SupT1 knockdown over many of the gene catalogs studied.

These results suggest that the 8.0 kb RNP fragment confers a substantial increase in the proportion of integration events that lead to detectable gene expression.

Furthermore, for TASK-1, we confirmed TM1 cross-linking to Sec61β from two different conformations/orientations of nascent chain, whereas nascent Kcv chains displayed unusually strong adducts with Sec61β, indicating that a substantial proportion of integration intermediates adopt an inverted topology.

Through their capacity to confer an increase in the proportion of integration events that are productive, together with improvements in the level of transgene expression, RNP CpG island vectors have many other potential applications, including use in mammalian cell-based in vitro screens for drug discovery, transgenic animals for basic research and drug discovery, and gene therapy.

These values were then plotted against the proportion of HIV integration sites in transcription units for that cell type (Figure 9).

In addition to these data on manipulated cell models, we also present additional bioinformatic studies of 15 published HIV integration site data sets in different cell types, which revealed a strong correlation between cell type specific LEDGF/p75 expression levels and the proportion of HIV integration sites in transcription units.

This is well within the distance from the ORF start codon that is likely to be cis regulatory sequence, and it seems likely that at least a proportion of these integrations have affected expression of downstream genes in some way.

Energy efficiency and larger proportion of renewable energy integration are treated as two of the solutions for electricity sector by governments, utilities as well as large end users.

Taken together, these data suggest that in at least a proportion of TASK-1 integration intermediates, TM1 has not adopted its correct topology even at a stage where P1 and TM2 have probably exited the ribosome and engaged the Sec61 complex (cf. Table 1).

No significant difference was observed between pre-infusion and post-infusion T-cells both in the frequency of integrations within genes (48% vs. 49%) and in the proportion of genes harboring integrations around the TSS (16.3% vs. 14.5%, p>0.1 in all comparisons) (Figure 1B).

The architects are themselves not exactly casual, with the result that the interiors are works of intense refinement, in which the relation of one rectangular room to another, proportion, the integration of air vents, the installation of LED lights whose colour can be adjusted and the tone and grain of the wooden floor have all been minutely considered.