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We found that if either excitatory or inhibitory MVST synapses were uniformly distributed throughout the dendritic tree, the proportion of inhibitory contacts in close proximity to excitatory contacts decreased.
In addition, the proportion of inhibitory GABA-ergic synapses stained positive for GAD67 was not substantially altered in neurons derived from Twin-DS-iPSCs.
Conversely, the proportion of inhibitory contacts onto GS (ankle) extensor motor neurons from V2b INs was higher than the proportion of V2b contacts onto their TA counterparts.
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The proportion of highly inhibitory samples was greatest in young children and decreased with age (3D7, P = 0.294 and W2mef, P = 0.006) (Table 1).
These data suggest that our stringent fourfold selection protocol yielded a high proportion of potent inhibitory shRNAs that are unique in their sequence preferences as compared to those predicted by publicly available design algorithms.
It is therefore expected that a proportion of the inhibitory inputs impinging on ganglion cells may already represent complex transformations of the visual signal.
An A-linked proanthocyanidin trimer molecule isolated from the CZ extract has shown to contain a significant proportion of this inhibitory activity [ 68].
In contrast, V2b-derived contacts represent a greater proportion of the inhibitory synapses onto extensor-related motor neurons as compared to antagonist flexor-related motor neurons.
In the current study, we show that the expression of miR-203 is epigenetically regulated by ING1b and that miR-203 mediates a significant proportion of the inhibitory effects of ING1b on cell proliferation.
Specifically, a higher proportion of the inhibitory contacts on flexor motor neurons come from V1 INs as compared to extensor motor neurons, whereas V2b INs preferentially contact motor neurons that innervate extensor muscles.
The proportion of apoptosis-inhibitory protein (Bcl-2) and apoptosis-promoting protein (Bax) determines the rate of apoptosis occurrence if cells are stimulated by apoptotic signals.
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