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Effective loci are defined as the number of independently segregating "loci" that would yield the same standard deviation of the proportion of genome shared among full-sibs as observed in real genomic data from human sib pairs [ 4].
In contrast, the larger proportion of genome with reproducible but low biochemical signal strength and less evolutionary conservation is challenging to parse between specific functions and biological noise.
The true proportion of genome shared, however, may deviate from this expectation [17].
Sequence complexity describes all the novel sequence information in a genome [reviewed in 27] and can be expressed as a proportion of genome size or in base pairs.
Secondly, relationship coefficient computed from a pedigree is an expectation of the proportion of genome shared identical by descent (IBD) under the infinitesimal model, assuming infinite number of unlinked loci.
The substantial difference in the frequency of chiasmata per chromosome per meiosis between Apis and Nasonia thus raises the question of whether it is caused by a chromosome-wide elevation of the recombination rates or by an increased proportion of genome regions with a high recombination frequency in the honeybee.
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According to this model, interference by defectors generated under enhanced mutagenesis is added to the increased proportion of genomes with lethal mutations that favor extinction through a reduction of viral load [46].
The MEDIPS R package was used to assess the proportion of genome-wide CpGs covered in each sample.
Recent studies suggest that noncoding RNAs (ncRNAs) constitute a large proportion of genome-encoded transcripts [ 14– 16].
Adherence to this threshold has served the field well, with a very high proportion of genome-wide significant signals withstanding replication.
The f i, R d proportion in genome-wide deleterious homozygotes within ROH consistently exceeded the f i, R n proportion of genome-wide non-deleterious homozygotes within ROH and the increasing slopes differed between deleterious and non-deleterious variants.
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