A novel quality function is used to determine the participation ratio for both CA and DE, and then a competitive selection takes place in order to select the proportion of function evaluations allocated for each technique.
These signatures include: 1) high proportion of function altering mutations; 2) reduction in genetic diversity; 3) high-frequency of derived alleles; 4) high genetic differentiation between populations; 5) long range haplotypes and strong linkage disequilibrium [16].
In the context of SNPs, the signature of positive selection includes a high proportion of function-altering mutations, site frequency spectrum with high frequency of the derived allele and low genetic diversity (as a signature of complete or partial sweep), different allele frequency between populations, and long haplotypes [ 26].
For each functional category, the proportions of function-related pathway pairs (FRPs) in intra- and inter-categories were compared.
The second is to carry out a higher proportion of processing functions within Kazakhstan by investing in oil refineries and petro-chemical plants.
In addition, the grafts created by the US team were only able to fulfil a small proportion of the functions of a normal liver.
In the case of the comparison between E. coli and E. carotovora, syntenic genes also covered a high proportion of essential functions, however, the first two positions were occupied by cofactor and nucleotide synthesis (see Additional file 13 panel c).
Since our hypothesis includes both, metabolic regulation through amino acids and morphogen signalling controlling the proportion of zonated functions, the implications for liver metabolism and pathology are very versatile.
Functional traits determined based on 16S rRNA genes showed categorical similarity with a recent skin metagenomic study (Fig. 1b), with a large proportion of the functions associated with carbohydrate, amino acid, vitamin, and nucleotide metabolism [ 15].
