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We calculated the Spearman correlation between the proportion of essential genes within a module and the correlation of k.in with essentiality and show that there is a strong positive correlation (r = 0.48).
Indeed, we found a positive association between gene essentiality and multifunctionality in our data set (Spearman's ρmultifunctionality vs. essentiality = 0.1689, P = 1.0 × 10−), that is, the proportion of essential genes is higher in highly multifunctional proteins.
In contrast, operons with high aggregation propensity encode a similar proportion of essential and nonessential proteins, 48% and 52% respectively (Table 1), suggesting that the sequences of essential bacterial cytoplasmic proteins suffer a stronger selection against deposition than those of nonessential ones, as previously proposed for different eukaryotic organisms [68].
The proportion of essential hypertensive patients prescribed BBs appear to decrease between 1995 and 2000; whereas the proportion of essential hypertensive patients prescribed ARBs appear to increase.
The proportion of essential genes is positively correlated with protein connectivity in mouse [ 9].
Hence, one would expect a higher proportion of essential genes in core proteins than attachment proteins.
We demonstrate that UEHGs are very likely to contain a large proportion of essential genes.
The proportion of essential medicines produced was not associated with manufacturer sales volumes.
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With high proportions of essential oil used, they showed high ability to reduce the rigidity of film or acted as plasticiser.
High proportions of essential fatty acids in all crab groups coupled with elevated levels of triacylglycerols in 12 °C animals, indicate that rapid growth does not negatively affect condition in juvenile RKC.
In addition, for genes categorized in other metabolism, the proportions of essential genes in this category were similar when cells were cultivated in both MG medium and YE medium, implying fewer alternatives routes for biosynthesis of some terpenoids and N-glycan in cell metabolic network.
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