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Haplogroups associated with longevity were identified as those with a larger proportion of enriched patterns out of the total number of patterns associated with the haplogroup.
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Examining all categories defined by the generic GO Slim subsets of biological processes, molecular functions, and cellular components confirms this difference among processes and functions whereas components instead exhibit similar proportions of enriched terms in the three lineages (supplementary table 5 and fig. 8, Supplementary Material online).
The idea is essentially to allow a proportion p21 of non-enriched probes in an enriched region and a proportion p12 of enriched probes in a non-enriched region.
As the zebrafish is not a close relative to our catfish and because the sequences of interest display high sequence divergence, a substantial proportion of the enriched library yielded no significant Blast matches.
However, relative to mice, human aging is distinguished by a dramatic increase in the proportion of neuron-enriched downregulated genes (Fig. 3).
As shown in Fig. 5B, this turned out to be the case since the proportion of progenitor-enriched c-kit+ BM cells in phase G0/G1 of the cell cycle was significantly higher among cells recovered from mice having received CB before stimulation with growth factor cocktail than among their saline-injected counterpart.
This relatively small proportion of gonadally-enriched mRNAs required for fertility may indicate significant genetic redundancy.
A higher proportion of HER2-enriched tumors was also observed in young patients.
The proportion of organ-enriched genes differentially expressed relative to wild type was determined.
This is significantly greater than the proportion of stamen-enriched genes identified as common to both microarray studies alone (approximately 49%).
In addition, a large proportion of the CNV-enriched classes have receptor and/or signaling functions.
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