Exact(13)
We found that the proportion of binding sites of either NHR within 5 kb of the TSS was significantly higher than downstream of a gene.
However, the fact that we could not detect a significant proportion of binding in the high affinity state in the human skin suggest that binding sites in high affinity state only represent a small proportion of total binding in the human skin.
We employed a one-tailed Fisher's Exact test to measure whether the proportion of binding sites of a motif inside the regions is higher than the proportion of binding sites in random regions.
For genes with higher expression levels the relative proportion of binding at non-specific sites is lower.
Large proportion of binding sites is located in certain positions in 3'-UTRs of corresponding SERCA2a and SERCA2b.
Removing BMH2, in contrast, removes a smaller proportion of binding partners for Rad53, thus resulting in a milder suppression effect on cdc13-1.
Similar(47)
Identifying lead HDAC inhibitor molecules in preclinical and translational research can be catalyzed using PET imaging with [C]martinostat, which demonstrated a high proportion of specific binding, with more than 60% of probe binding in brain prevented in homologous ([C]martinostat) and heterologous (CN54) in vivo blocking experiments.
This study demonstrated that where the proportion of HB binding sperm is ≤65%, sperm selection by hyaluronan binding resulted in a statistically significant decrease in PLR and promising although not significant improvements in IR and CPR.
The relative proportion of DNA binding was calculated by dividing the proportion of DNA binding in the ChIP for a single region by the average recovered for all regions for that chromatin to normalize for plate plate differences.
To study ligand binding in multiple conformations, it was necessary to estimate the proportion of ligand binding in each position.
Between the genomic region of 2 genes, the proportion of STAT1 binding sites of double promoters was higher than other 3 promoter categories, which indicates that these STAT1 binding sites are important in recruiting RPol II for both genes.
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