In L2, the proportion of Arc-expressing cells also differed significantly between CC and SE animals (F1,33 = 14.509, p<0.001) 29.56% of the BrdU-positive cells expressing Arc from the CC group were located in L2 as compared to 1.67% from the SE animals.
One-way ANOVA with Bonferroni as a Post-hoc test, MANOVA, or a student's t-test was used where appropriate to compare the proportion of BrdU-positive, Arc-expressing, and BrdU-positive Arc-expressing cells in the different conditions and throughout the DG granular layer.
The proportion of DG neurons expressing Arc after exploration was 1.5%, significantly higher than that observed in the cage control animals and in agreement with the notion of a sparse code for spatial information processing in the DG [22], [26], [27].
The position of the BrdU-positive cells expressing Arc within the different granular layers of the dentate gyrus [8] was identified, and for each layer we calculated the proportion of BrdU-positive cells expressing Arc relative to the total population of BrdU-positive cells that express Arc.
In our case, from day 1 until day 15 PBI the proportion of BrdU-positive cells expressing Arc was similar in cage control and exploration animals.
The MANOVA analysis revealed significant differences between the various layers in the proportion of BrdU-positive cells expressing Arc (Wilks lambda F2,31 = 7.183, p<0.01), and it is clear that the L1 region had the highest Arc expression in BrdU-positive cells.
LIMD1 depletion increased stress fibres and/or cortical F-actin bundles in a proportion of cells, somewhat similar to ARC depletion.
The proportion of cells that was Arc as well as the intensity of Arc immunoreactivity were similar between the N15 and N60 groups (Fig. 1 B, C ).
Consider the labels on the arcs as the proportion of the available bandwidth for the node compared to the available bandwidth on the nodes from the candidate set.
