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Employing sequences from a candidate gene and the 1000 Genomes Project, Fridley et al. (2010) demonstrated the feasibility of imputing genetic variants based on a sequenced proportion of a study sample, and they suggested sequencing "the largest and most diverse" subset.
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The previous studies mentioned used telephone interview or mail questionnaire methods to sample a small proportion of a large study population.
Obviously, the lack of ER evaluation in a relevant proportion of the study population represents a major limitation of the study.
Furthermore, this group represents only a limited proportion of the study population and a larger number of patients may have influenced the results.
A considerable proportion of our study population with a positive history of childhood vaccination for pertussis was not serologically immune to pertussis.
A considerable proportion of the study population with a positive history of childhood vaccination for pertussis was not serologically immune to pertussis.
Probably, our findings could be attributed to the fact that a large proportion of the study participants had a high level of education.
A weak point in this study was that a relatively large proportion of the study population was not a regular visitor to the company canteen (about 40%).
However, survival data of a considerable proportion of the study patients were obtained from the family register database.
Also, information regarding CRD status was incomplete for a proportion of the study sample.
Additionally, we had information on prostate volume and BMI for a proportion of our study population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com