For serious IRRs, a 1-sided 95% exact confidence upper limit of the proportion was provided.
Similar estimations of stromal cell proportion were provided for rat (Schmalbruch & Hellhammer, 1977) and mice (Murray & Robbins, 1982) skeletal muscles.
Although the correct admixture proportion was provided to all the methods, we note that it can easily be estimated by other methods such as Frappa (Tang et al., 2005).
A study sample of n = 360 from a potential population of 5500 allowed estimation with 95%% confidence intervals of a population proportion being provided with GWG guidelines with precision of approximately 5 % and estimation of a population mean with precision of approximately 10%% of the population standard deviation.
The special case that no label proportions are provided in the training data (degraded to naive GL) is also considered, denoted by σ= max.
Besides, if no label proportions are provided (i.e., p k =1, k=1,…,K as defined in Naive GL), our method can still work relatively well, outperforming GL+SVM about 1% in classification accuracy (see the case of σ= max in Fig. 7).
Finally, the comparison analysis between the possibilistic entropy model and the proportion entropy model is provided by two numerical examples to illustrate the efficiency of the proposed approaches and the designed algorithm.
A broader, non-parametric justification why AUC is more discriminative than proportion of misclassifications is provided by [29].
Since methylated as well as unmethylated DNA is amplified, information on the proportion of both is provided.
Each institution of the DECCA database with its respective contributing proportion of patients is provided in Additional file 1.
